Cutaneous abscess / furunculosis
Boil ยท furuncle ยท carbuncle (multiple coalescing) ยท skin abscess
A cutaneous abscess is a localised collection of pus within the dermis or subcutaneous tissue, most commonly caused by Staphylococcus aureus (including MRSA). A furuncle (boil) is a deep follicular abscess; a carbuncle is a coalescing group of furuncles. Management is principally incision and drainage (I&D); antibiotics are reserved for surrounding cellulitis, systemic features, immunosuppression and high-risk anatomy. UK antimicrobial decisions should follow NICE CKS for boils / carbuncles and NICE NG141 when cellulitis or erysipelas is present.
Microbiology
- Staphylococcus aureus โ predominant; including community MRSA (PVL+ carriers).
- Polymicrobial in anogenital / perineal / axillary settings; anaerobes (Bacteroides, Peptostreptococcus).
- Hidradenitis suppurativa: chronic recurrent flexural abscesses; specialised pathway.
- Risk factors: diabetes, obesity, immunosuppression, IV drug use, atopic eczema, S. aureus nasal carriage.
Clinical features
- Tender, erythematous, fluctuant nodule with surrounding induration.
- Spontaneous pointing / pustule formation common.
- Sites: face, neck, axillae, groin, buttocks, thighs.
- Furuncle: deep follicular abscess; commonly hair-bearing sites.
- Carbuncle: cluster of communicating furuncles; deeper involvement; often diabetic / immunosuppressed; back of neck classic.
- Hidradenitis suppurativa abscess: chronic; flexural; sinus tract formation.
- Complications: cellulitis, lymphangitis, bacteraemia, sepsis, endocarditis (rare), facial / nasal-triangle thrombophlebitis.
Investigations
- Clinical diagnosis usually adequate.
- USS confirms collection if uncertain about fluctuance.
- Pus swab on I&D for culture & sensitivity (especially MRSA screening, recurrent disease).
- Nasal / axillary / groin swab if recurrent (S. aureus carrier).
- Bloods (FBC, CRP, U&E, glucose) if systemic features or comorbid.
- HIV, immunoglobulins for unusual / atypical recurrent abscesses.
Management
- Incision and drainage (I&D) โ primary intervention:
- Local anaesthetic with adrenaline (or field block).
- Incise along Langer lines / RSTL; ensure adequate drainage.
- Pus swab for culture.
- Loculation breakdown with finger / forceps.
- Wound packing (hypertonic saline / Aquacel ribbon / iodoform gauze) for large cavities; daily change; alternatively loop drainage technique for thigh / buttock.
- Antibiotics adjunct only if clinically indicated:
- Surrounding cellulitis / extensive infection.
- Systemic features (fever, malaise, raised inflammatory markers).
- Immunosuppression, diabetes, comorbidity.
- Recurrent disease.
- Facial / perineal / hand abscess.
- First-line oral: flucloxacillin 500 mg QDS for 5-7 days.
- Penicillin-allergic: clarithromycin / erythromycin / doxycycline.
- MRSA: doxycycline 100 mg BD, co-trimoxazole, clindamycin 300-450 mg QDS.
- Recurrent disease:
- Decolonisation: nasal mupirocin 2% BD ร 5 days + chlorhexidine 4% body wash ร 5-7 days.
- Treat household members concurrently.
- Address risk factors: BMI, smoking, glycaemic control.
- Hidradenitis suppurativa: dedicated pathway; antibiotic (e.g. doxycycline / clindamycin + rifampicin), adalimumab / secukinumab; deroofing / excision.
- Carbuncle: hospital admission for IV antibiotics in selected cases; surgical debridement.
References
- NICE Clinical Knowledge Summary. Boils, carbuncles, and staphylococcal carriage. London: NICE; accessed 18 May 2026.
- NICE NG141. Cellulitis and erysipelas: antimicrobial prescribing. London: NICE; 2019.
- Stevens DL et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections. Clin Infect Dis. 2014;59:e10-e52.
- Singer AJ, Talan DA. Management of skin abscesses in the era of methicillin-resistant Staphylococcus aureus. N Engl J Med. 2014;370:1039-1047.
- British Association of Dermatologists. UK guidelines for the management of hidradenitis suppurativa. Br J Dermatol. 2019;180:1009-1017.
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